HLA-DRB1*0407 and *1304 are risk factors for scleroderma renal crisis
نویسندگان
چکیده
منابع مشابه
HLA-DRB1*0407 and *1304 are risk factors for scleroderma renal crisis.
OBJECTIVE To examine the predictive role of HLA genetic markers in scleroderma renal crisis (SRC), beyond the known clinical correlates, in a large population of patients with systemic sclerosis (SSc). METHODS SSc patients from the Scleroderma Family Registry and DNA Repository, the Genetics versus Environment in Scleroderma Outcomes Study, and the rheumatology division registry at the Univer...
متن کاملScleroderma Renal Crisis
Scleroderma renal crisis (SRC) is an infrequent complication of a rare disease. To date, many aspects of the pathophysiology of SRC are still mysterious. Since SRC biopsies are not frequently encountered in practice, our understanding of the spectrum of histologic changes is derived from a combination of a limited personal experience and data obtained from several relatively small pathologic st...
متن کاملIntriguing presentation of scleroderma renal crisis (scleroderma renal crisis sine scleroderma sine hypertension).
Key words: systemic sclerosis; scleroderma renal crisis; to complain of arthralgia affecting mainly her wrists sine scleroderma; sine hypertension and small joints of the hands. For the last several months she had experienced difficulty in swallowing and anorexia with a resultant weight loss of 20 kg. Despite these symptoms, she did not seek medical
متن کاملRenal complications and scleroderma renal crisis.
Scleroderma renal crisis (SRC) occurs in 5-10% of SSc patients, who may present with an abrupt onset of hypertension, acute renal failure, headaches, fevers, malaise, hypertensive retinopathy, encephalopathy and pulmonary oedema. Patients at greatest risk of developing SRC are those with diffuse cutaneous or rapidly progressive forms of SSc, and treatment with a recently commenced high dose of ...
متن کاملScleroderma renal crisis sine scleroderma in pregnancy: a case report.
Scleroderma renal crisis has been documented as the presenting manifestation of systemic sclerosis sine scleroderma in pregnancy only once in the literature. Unfortunately, since scleroderma renal crisis in sine scleroderma pregnant patients is so rare, that patient expired. We present a case of a sine scleroderma pregnant patient with an initial manifestation of scleroderma renal crisis surviv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2011
ISSN: 0004-3591
DOI: 10.1002/art.30111